Summary 
A Consensus Conference on Colon and Rectal Cancer was held at the National Institutes of Health in April 1990. The treatment recommendations of the panel were:

1. Stage I Colon and Rectal 
    No adjuvant therapy is warranted, since there is a low risk of recurrence .

2. Stage II Colon 
    Specific adjuvant therapy cannot be recommended routinely for intermediate-risk tumors outside a clinical
    trial. Those with larger tumors (T3 or T4), an elevated preoperative CEA level, poorly differentiated tumors
    and abnormal DNA, are candidates for adjuvant chemotherapy .

3. Stage III Colon 
    There is a high risk for recurrence, and treatment with levamisole and 5-FU is recommended.

4. Stages II and III Rectal 
    Adjuvant combined radiotherapy and chemotherapy is recommended postoperatively. This will improve local
    control and survival.